Clean single-source support for Python 3 and 2

https://python-future.org/

Module designed to write games in Python

https://www.pygame.org/news

Python bindings to the GNU dbm library (Python 3.10)

Toolkit for generation of output for the web

https://genshi.edgewall.org/

Documentation generator for GObject-based libraries

https://gitlab.gnome.org/GNOME/gi-docgen

Git Object Database

https://pypi.org/project/gitdb2/

Python Git Library

https://github.com/gitpython-developers/GitPython

Bridge from Glyphs source files (.glyphs) to UFOs

https://github.com/googlei18n/glyphsLib

Python Extension that Wraps the GMP Library

http://code.google.com/p/gmpy/

GMP/MPIR, MPFR, and MPC interface to Python

https://pypi.org/project/gmpy2/

Common files for the Python bindings for GObject

Build and validate addresses in localized formats

https://pypi.org/project/google-i18n-address/

Free Google Translate API that translates totally free of charge

https://github.com/ssut/py-googletrans

Library/CLI tool to interface with Google Translate text-to-speech API

https://github.com/pndurette/gTTS

WSGI HTTP Server for UNIX

https://gunicorn.org/

Build System That Generates Other Build Systems

https://gyp.gsrc.io/

Pure-Python, bring-your-own-I/O implementation of HTTP/1.1

https://pypi.org/project/h11/

HTTP/2 State-Machine based protocol implementation

http://hyper.rtfd.org/

Classes and setuptools plugin for Mercurial repositories

https://github.com/jaraco/hgtools

Python extension that wraps hiredis

https://github.com/pietern/hiredis-py

HTTP/2 header encoding (HPACK) logic implementation

http://hyper.rtfd.org/

Chromium HSTS Preload list

https://github.com/sethmlarson/hstspreload

Python based HTML parser based on the HTML5 spec

https://github.com/html5lib

HTTP Request & Response Service

https://github.com/postmanlabs/httpbin

Minimal low-level HTTP client

https://github.com/encode/httpcore

Comprehensive HTTP client library

https://github.com/httplib2/httplib2

Next generation HTTP client

https://github.com/encode/httpx

Python module that decodes binary streams into HTTP/2 frames

http://hyper.rtfd.org/

Featureful, correct URL for Python

https://github.com/python-hyper/hyperlink

Library for property based testing

https://github.com/HypothesisWorks/hypothesis/tree/master/hypothesis-python

Internationalized Domain Names in Applications (IDNA)

https://github.com/kjd/idna

Patch ssl.match_hostname for Unicode(idna) domains support

https://pypi.org/project/idna_ssl/

Python image size library

https://github.com/shibukawa/imagesize_py

Read metadata from Python packages

https://github.com/python/importlib_metadata

Library that versions your Python projects

https://pypi.org/project/incremental/

Editable interval tree data structure for Python 2 and 3

https://github.com/chaimleib/intervaltree

Python task execution tool & library

https://github.com/pyinvoke/invoke

Google open source IPv4/IPv6 manipulation library in Python

https://github.com/google/ipaddr-py

Simple module to parse ISO 8601 dates

https://bitbucket.org/micktwomey/pyiso8601

ISO 8601 date/time/duration parser and formater

https://pypi.org/project/isodate/

Python import sorter utility

https://github.com/PyCQA/isort

Various helpers to pass data in untrusted environments

https://github.com/mitsuhiko/itsdangerous/

Shared namespace shim for py-jaraco.* ports

Python class routines

https://github.com/jaraco/jaraco.classes

Low-level, pure Python DBus protocol wrapper

https://gitlab.com/takluyver/jeepney

JSON Matching Expressions

https://github.com/jmespath/jmespath.py

JOSE protocol implementation in Python

https://josepy.readthedocs.io/en/latest/

Implementation of JSON Reference for Python

https://pypi.org/project/jsonref/

Store and access your passwords safely

https://github.com/jaraco/keyring

Alternate Python keyring implementations

https://pypi.org/project/keyrings.alt/